Biostimulant Injectables

Calcium Hydroxyapatite (CaHA)

What Is It?

A biostimulant containing calcium hydroxyapatite in the form of microspheres.

Mechanism of Action

• Provides mild volume at first
• Stimulates fibroblasts over time
• Increases type I collagen production

Areas of Use

• Midface and jawline contour
• Neck and décolleté
• Back-of-hand rejuvenation
• Improving skin quality (in diluted form)

Duration of Effect

• Volume effect: immediate
• Biostimulation: becomes more apparent in 2-3 months
• Duration: approximately 12-18 months

Advantages

• Both immediate and biological effect
• Strong lifting support
• Fewer sessions

 Poly-L-Lactic Acid (PLLA)

What Is It?

A synthetic polymer used entirely for biostimulation purposes.

Mechanism of Action

• The initial volume effect is minimal
• Progressive collagen increase through fibroblast activation
• Dermal thickening

Areas of Use

• Widespread volume loss
• Temporal region
• Cheeks and lower face
• Body areas (buttocks, arms, etc.)

Duration of Effect

• Onset: 4-6 weeks
• Best results: 3-6 months
• Duration: up to 2 years

Advantages

• Very natural and gradual result
• Ideal for larger areas
• Long-lasting effect